SYNTHESIS OF 7-METHYL-6-(NITROIMIDAZOLYL)THIOPURINES

Authors

  • П. М. Кочергин Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow
  • E. В. Александрова Zaporozhye State Medical University
  • В. C. Корсунский Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow
  • В. C. Шлихунова Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow

DOI:

https://doi.org/10.1007/49

Keywords:

thiopurines, chloropurines, nitrohaloimidazoles, nitromercaptoimidazoles, nitroimidazolylthiopurines

Abstract

We have studied the reactions of 7-methyl-6-thiopurine with 5(4)-halo-4(5)-nitroimidazoles and 6-chloro-7-methylpurine with sodium and ammonium salts of 5-mercapto-4-nitroimidazoles. We have obtained a series of 7-methyl-6-(nitroimidazolyl)thiopurines not previously described in the literature.

Authors: P. M. Kochergin, E. V. Aleksandrova, V. S. Korsunskii, and V. S. Shlikhunova.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (2), pp 178-181

http://link.springer.com/article/10.1007/BF02283548

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Published

2012-11-16

Issue

No. 2 (2000)

Section

Original Papers