3-AMINO-4-[5-(CHLOROMETHYL)-1,2,4-OXADIAZOL-3-YL]FURAZAN - A MULTIFUNCTIONAL SYNTHON FOR THE SYNTHESIS OF 1,2,5-OXADIAZOLE DERIVATIVES

Authors

  • Андрей И. Степанов Special Design and Technology Bureau ''Technolog'', 33a Sovetsky Ave., Saint Petersburg 192076, Russia
  • Дмитрий В. Дашко Special Design and Technology Bureau ''Technolog'', 33a Sovetsky Ave., Saint Petersburg 192076, Russia
  • Елена В. Степанова North-Western State Medical University named after I. I. Mechnikov, 41 Kirochnaya St., Saint Petersburg 191015, Russia

DOI:

https://doi.org/10.1007/4926

Keywords:

chloromethyl, furazan, 1, 2, 4-oxadiazole, 5-oxadiazole, oxidation.

Abstract

The chemical properties of 3-amino-4-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]furazan were scrutinized: acylation of the amino group and its oxidation to azo and nitro groups, reactions of the chloromethyl group with N- and S-nucleophilic reagents, as well as reactions of transformation of the 1,2,4-oxadiazole ring.

Author Biographies

Андрей И. Степанов, Special Design and Technology Bureau ''Technolog'', 33a Sovetsky Ave., Saint Petersburg 192076, Russia

к.х.н., начальник технологической лаборатории

Дмитрий В. Дашко, Special Design and Technology Bureau ''Technolog'', 33a Sovetsky Ave., Saint Petersburg 192076, Russia

к.х.н., нач. отдела

Елена В. Степанова, North-Western State Medical University named after I. I. Mechnikov, 41 Kirochnaya St., Saint Petersburg 191015, Russia

к.г.н., доц. каф. химии

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Published

2019-12-18

Issue

Vol. 55 No. 12 (2019)

Section

Original Papers