AN EXPEDITIOUS ULTRASOUND-INITIATED GREEN SYNTHESIS OF 1,2,4-THIADIAZOLES IN WATER

Authors

  • Swati Chauhan Department of Chemistry, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005, India
  • Pratibha Verma Department of Chemistry, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005, India
  • Ankush Mishra Department of Chemistry, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005, India
  • Vandana Srivastava Department of Chemistry, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005, India

DOI:

https://doi.org/10.1007/5043

Keywords:

aqueous medium, heterocycles, metal- and catalyst-free, one-pot synthesis, oxidative coupling, ultrasound irradiation.

Abstract

A convenient, environmentally benign, metal- and catalyst-free protocol has been developed for the conversion of thioamides to the corresponding 1,2,4-thiadiazole derivatives with chloranil under ultrasound irradiation in water at room temperature. This paper describes a general procedure for the synthesis of different 1,2,4-thiadiazoles in excellent yield in short reaction time via sonochemistry.

Downloads

Published

2020-01-31

Issue

Vol. 56 No. 1 (2020)

Section

Short Communications