HETEROCYCLIZATION OF ALICYCLIC 1,5-DIKETONES. SYNTHESIS OF <i>N</i>-SUBSTITUTED 5-(4,5,6,7-TETRAHYDRO-1<i>H</i>-INDOL-2-YL)PENTANOIC ACIDS ON THE BASIS OF (2,2'-METHANEDIYL)BISCYCLOHEXANONE AND PRIMARY AMINES
Authors
Константин В. Маслов
Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
Олег Ю. Слабко
Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
Александр Н. Андин
Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
Юлия В. Худякова
G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences,
159 100-letiya Vladivostoka Ave., Vladivostok 690022, Russia
Владимир А. Каминский
Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
The bisulfite adduct, formed upon treatment of (2,2'-methanediyl)biscyclohexanone with aqueos sodium bisulfite solution in the presence of acetic acid, subsequently reacted under the same conditions with certain aromatic and aliphatic primary amines, giving moderate yields of N-substituted 5-(4,5,6,7-tetrahydro-1H-indol-2-yl)pentanoic acids.
Author Biographies
Константин В. Маслов, Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
Инженер кафедры органической химии
Олег Ю. Слабко, Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
к.х.н., доцент кафедры органической химии
Александр Н. Андин, Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
к.х.н., доцент кафедры органической химии
Юлия В. Худякова, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences,
159 100-letiya Vladivostoka Ave., Vladivostok 690022, Russia
к.б.н., н.с.,
Владимир А. Каминский, Far Eastern Federal University,
k. L Universitetsky Ave., Russky Island, Vladivostok 690622, Russia
