A PERSPECTIVE ON ENVIRONMENTALLY BENIGN PROTOCOLS OF THIAZOLE SYNTHESIS

Authors

  • Arnab Chowdhury Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India
  • Sagarkumar Patel Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India
  • Ayushi Sharma Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India
  • Anwesha Das Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India
  • Payal Meshram Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India
  • Amit Shard Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India

DOI:

https://doi.org/10.1007/5456

Keywords:

thiazole, biodegradable chemicals, catalyst-free synthesis, environment-friendly synthesis, green synthesis, solvent-free synthesis.

Abstract

Thiazole has widespread importance in materials and medicines. Several reviews are reported which cover essential properties of thiazoles such as pharmacological activities, structure-activity relationship studies, and various synthetic routes. However, synthesis based on a greener approaches, particularly metal-free reactions, usage of mild, nontoxic, recyclable catalysts, eco-sustainable protocols, efficient solvents have not been exclusively reviewed. Current review emphasizes green synthetic approaches for substituted thiazoles that have been performed within the last decade.

Author Biography

Amit Shard, Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Ahmedabad, Palaj, Gandhinagar 382355, Gujarat, India

Amit Shard, Ph.D

Assistant Professor,

Department of Medicinal Chemistry,

National Institute of Pharmaceutical Education and Research (NIPER),

Ahmedabad (An Institute of National Importance, Govt. of India)

Website:http://www.niperahm.ac.in

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Published

2020-04-30

Issue

Vol. 56 No. 4 (2020): Green chemistry of heterocycles

Section

Review Articles