MULTICOMPONENT SYNTHESIS OF NICOTINIC ACID DERIVATIVES

Authors

  • Иван В. Дяченко Luhansk Taras Shevchenko National University, 2 Oboronna St., Lugansk 91000, Ukraine
  • Владимир Д. Дяченко Luhansk Taras Shevchenko National University, 2 Oboronna St., Lugansk 91000, Ukraine
  • Павел В. Дороватовский National Research Center ''Kurchatov Institute'', 1 Akademika Kurchatova Sq., Moscow 123182, Russia
  • Виктор Н. Хрусталев RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russia; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
  • Валентин Г. Ненайденко Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow 119991, Russia

DOI:

https://doi.org/10.1007/5891

Keywords:

6-alkoxy-2-alkylsulfanyl-4-methyl(4, 4-dimethyl)nicotinic acid, СH acids, thiazolo[3, 2-a]pyridines, alkylation, Michael reaction, multicomponent synthesis, X-ray structural analysis.

Abstract

The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis.

Author Biographies

Иван В. Дяченко, Luhansk Taras Shevchenko National University, 2 Oboronna St., Lugansk 91000, Ukraine

доцент кафедры химии и биохимии

Владимир Д. Дяченко, Luhansk Taras Shevchenko National University, 2 Oboronna St., Lugansk 91000, Ukraine

Заведующий кафедрой химии и биохимии, д.х.н., проф.

Павел В. Дороватовский, National Research Center ''Kurchatov Institute'', 1 Akademika Kurchatova Sq., Moscow 123182, Russia

Научный сотрудник, к.х.н.

Виктор Н. Хрусталев, RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russia; N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia

д.х.н., проф.

Валентин Г. Ненайденко, Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow 119991, Russia

Завкафедрой органической химии, д.х.н., проф.

Published

2020-12-18

Issue

Section

Original Papers