REGIOSELECTIVITY IN THE REACTION OF PARAFORMALDEHYDE WITH (1S,2S)-2-ARYL(HETARYL)METHYLAMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOLS
DOI:
https://doi.org/10.1007/596Abstract
The reaction of paraformaldehyde with (1S,2S)-2-aryl(hetaryl)methylamino-1-(4-nitrophenyl)-1,3-propanediols produces a mixture of isomeric 3-aryl(hetaryl)methyl-4-hydroxymethyl-5-(4-nitrophenyl)- and 3-aryl(hetaryl)methyl-4-hydroxy(4-nitrophenyl)methyloxazolidines and is reversible.
Authors: J. Couquelet, M. Madesclaire, F. Leal, V. P. Zaitsev, and S. Kh. Sharipova.
English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (4), pp 474-478