POLYFLUOROALKYLATION AND ALKENYLATION OF 1-BENZYL-1H-INDAZOL-3-OL

Authors

  • Т. М. Соколенко Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094
  • Л. М. Ягупольский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

DOI:

https://doi.org/10.1007/6147

Keywords:

dibromodifluoromethane, 1, 2-dibromotetrafluoroethane, 2-dichlorodifluoroethylene, chlorodifluoromethane, 1-difluoroethylene, indazol-3-ol, tetrafluoroethylene, 2-trichlorotrifluoroethane, chlorotrifluoroethylene, polyfluoroalkylation, fluoroalkenylation

Abstract

The polyfluoroalkylation and alkenylation of 1-benzyl-1H-indazol-3-ol by halopolyfluoroalkanes and fluorinated olefins has been studied. It was shown that only reactions proceeding with the participation of difluorocarbene lead to a mixture of N- and O-alkylation products. In all other cases, interaction with halopolyfluoroethanes and polyfluoroalkenes forms O-polyfluoroalkyl and alkenyl derivatives of indazolol.

How to Cite
Sokolenko,  T. M.; Yagupolskii, L. M. Chem. Heterocycl. Compd. 2011, 46, 1335. [Khim. Geterotsikl. Soedin. 2010, 1649.]

For this article in the English edition see
DOI 10.1007/s10593-011-0670-y

 

 

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Published

2021-02-10

Issue

No. 11 (2010)

Section

Original Papers