SYNTHESIS OF IMIDAZO[1,2-<i>a</i>]PYRAZINE AND IMIDAZO[1,2-<i>a</i>]PYRIMIDINE DERIVATIVES
DOI:
https://doi.org/10.1007/617Keywords:
2-aminoimidazole, imidazo[1, 2-a]pyrazines, 2-a]pyrimidines, catalytic hydrogenationAbstract
Synthetic approaches to the construction of bicyclic systems containing the imidazole nucleus have been considered. Methods for obtaining derivatives of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine have been studied, and methods have been developed for catalytic hydrogenation of these compounds. Partial reduction of the imidazole ring on imidazo[1,2-a]pyrimidine hydrogenation has been discovered for the first time.
Authors: A. V. Borisov, A. A. Tolmachev, O. A. Zavada, I. A. Zhuravel', and S. N. Kovalenko
English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (5), pp 704-711