BIFUNCTIONALIZATION OF A MIXTURE OF 2-CHLORO- AND 2-BROMO-<i>N</i>-ETHOXYCARBONYLMETHYLPYRIDINIUM HALIDES BY ARYLMETHYLIDENEMALONONITRILES IN BASIC MEDIUM
DOI:
https://doi.org/10.1007/618Keywords:
2-chloropyridinium salts, 2-bromopyridinium salts, 2-dicyanomethylidene-1, 2-dihydro-pyridine, ethyl 2-amino-1-cyanoindolizine-3-carboxylateAbstract
The two-component condensation of 2-chloro- or 2-bromo-N-ethoxycarbonylmethylpyridinium halides and aryl- or hetarylmethylidenemalononitriles gave ethyl 2-[2-(dicyanomethylidene)pyridin-1(2H)-yl]-3-arylacrylates. Correlation NMR spectroscopy and X-ray diffraction structural analysis allowed the structural characterization of these products.
Authors: N. M. Tverdokhleb, G. E. Khoroshilov, R. I. Zubatyuk, and O. V. Shishkin
English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (5), pp 720-725