REACTION OF ARYLIDENE DERIVATIVES OF MELDRUM'S ACID WITH 3-AMINO-1,2,4-TRIAZOLE

Abstract

The condensation of arylidene derivatives of Meldrum's acid with 3-amino-1,2,4-triazole in nitrobenzene leads to 4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-5-ones. In DMF the reaction proceeds with the formation of arylsubstituted N-(2H-1,2,4-triazol-3-yl)-3-(2H-1,2,4-triazol-3-ylamino)propionamides.

Authors: V. V. Lipson, V. D. Orlov, S. M. Desenko, T. M. Karnozhitskaya, and M. G. Shirobokova.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (5), pp 595-599

http://link.springer.com/article/10.1007/BF02324645