4-HYDROXY-2-QUINOLONES. 170. SYNTHESIS AND BROMINATION OF N-ALLYLISATIN

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Н. Л. Березнякова National University of Pharmacy, Kharkiv 61002
  • О. В. Горохова National University of Pharmacy, Kharkiv 61002
  • С. В. Шишкина Institute for Single Crystal, National Academy of Sciences of Ukraine, Kharkiv 61001

DOI:

https://doi.org/10.1007/6565

Keywords:

N-allylisatin, alkylation, bromination, halocyclization, X-ray structural analysis

Abstract

Independently of the reaction conditions N-allylisatin forms only the 2,3-dibromo derivative upon treatment with molecular bromine in contrast to N-allyl-substituted quinolin- or pyrid-2-ones which readily undergo halocyclization to the corresponding 2-bromomethyl oxazoles.

How to Cite
Ukrainets, I. V.; Bereznyakova, N. L.; Gorokhova, O. V.; Shishkina, S. V.  Chem. Heterocycl. Compd. 2009, 45, 1241. [Khim. Geterotsikl. Soedin. 2009, 1546.]

For this article in the English edition see DOI 10.1007/s10593-010-0413-5

 

Published

2022-02-10

Issue

Section

Original Papers