CONDENSED ISOQUINOLINES. 34. TRANSFORMATIONS OF 4H-THIENO[3',2':5,6]- AND 4H-THIENO[2',3':5,6]PYRIMIDO[1,2-<i>b</i>]ISOQUINOLINES
DOI:
https://doi.org/10.1007/6760Keywords:
derivatives of the 4H-thieno[3', 2', 5, 6]- and 4H-thieno[2', 3', 6]pyrimido[1, 2-b]isoquinoline systems, positional isomers, nucleophilic substitution, calculation of biological activityAbstract
Syntheses are given for previously unreported 4-chloro derivatives of 4H-thieno[3',2':5,6]- and 4H-thieno[2',3':5,6]pyrimido[1,2-b]isoquinolines and the reactions of these compounds with N- and S-nucleophiles were studied. The spectral characteristics and biological activity of the positional isomers were compared. The electron spectra most clearly reflect the differences related to the position of the sulfur atom in these quasiaromatic systems.
How to Cite
Zadorozny, A. V.; Kovtunenko, V. A. Chem. Heterocycl. Compd. 2009, 45, 489. [Khim. Geterotsikl. Soedin. 2009, 619.]
For this article in the English edition see DOI 10.1007/s10593-009-0288-5
