UNEXPECTED CYCLIZATION ROUTE FOR <i>o</i>-ETHYNYLBENZOIC ACIDS HYDRAZIDES IN THE PRESENCE OF BASE
DOI:
https://doi.org/10.1007/6879Keywords:
arylacetylenes, benzopyridazinones, ethynylbenzoic acids esters, isoindolinones, heterocyclization, cross coupling, reactions with hydrazineAbstract
The reaction of o-ethynylbenzoic acids hydrazides with base has been studied. In the presence of a strong donor substituent (1,5-dimethylpyrazol-4-yl) it has been found that an unusual cyclization route occurs to give the corresponding benzopyridazinone instead of the expected isoindolinone.
How to Cite
Vasilevsky, S. F.; Mikhailovskaya, T. F. Chem. Heterocycl. Compd. 2009, 45, 55. [Khim. Geterotsikl. Soedin. 2009, 67.]
For this article in the English edition see DOI 10.1007/s10593-009-0225-7