HETEROCYCLES WITH A BRIDGING NITROGEN ATOM. 19. DEVELOPMENT OF ROUTES FOR THE SYNTHESIS OF OXAZOLOISOQUINOLINIUM SALTS BASED ON PHENACYLATION OF α-METHYL-1(3)-ISOQUINOLONES
DOI:
https://doi.org/10.1007/6897Keywords:
1-isoquinolone, isoquinol-3-one, bridging oxazoloquinolines, O, N-alkylationAbstract
Alkylation of 3-methyl-1-isoquinolone and 1-methyl-3-isoquinolone with phenacyl bromides proceeds regioselectively with the formation in the first case of only an N-phenacyl derivative and in the second
only the O-derivative. The 5-methyl[1,3]oxazolo[3,2-a]isoquinolinium salt has been synthesized and its reactions with ammonia, morpholine, and sodium methylate have been investigated.
How to Cite
Babaev, E. V.; Nevskaya, A. A.;Dlinnykh, I. V.; Rybakov, V. B. Chem. Heterocycl. Compd. 2009, 45, 93. [Khim. Geterotsikl. Soedin. 2009, 110.]
For this article in the English edition see DOI 10.1007/s10593-009-0231-9