4-HYDROXY-2-QUINOLONES. 150. EFFICIENT SYNTHESIS, STRUCTURE, AND BIOLOGICAL ACTIVITIES OF 4-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ALKYL AMIDES

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Н. Л. Березнякова National University of Pharmacy, Kharkiv 61002
  • В. А. Паршиков National University of Pharmacy, Kharkiv 61002
  • О. В. Горохова National University of Pharmacy, Kharkiv 61002

DOI:

https://doi.org/10.1007/7301

Keywords:

diuretics, 4-methyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid, amidation, X-ray structural analysis

Abstract

A simple and efficient method for preparing 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkyl amides is proposed. The results of a study of the diuretic activity of the compounds synthesized are reported.

How to Cite
Ukrainets, I. V.; Bereznyakova, N. L.; Parshikov, V. A.; Gorokhova, O. V.  Chem. Heterocycl. Compd. 2008, 44, 1493. [Khim. Geterotsikl. Soedin. 2008, 1841.]

For this article in the English edition see DOI 10.1007/s10593-009-0209-7


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Published

2023-01-05

Issue

No. 12 (2008)

Section

Original Papers