INTERACTION OF AMINOAZOLES WITH MELDRUM'S ACID AND DIALKYL KETONES OR CYCLOHEXANONE

Authors

  • В. В. Липсон V. Ya. Danilevsky Institute of Endocrine Pathology Problems, Academy of Medical Sciences of Ukraine, Kharkiv 61002
  • В. В. Бородина V. Ya. Danilevsky Institute of Endocrine Pathology Problems, Academy of Medical Sciences of Ukraine, Kharkiv 61002
  • М. Г. Широбокова V. Ya. Danilevsky Institute of Endocrine Pathology Problems, Academy of Medical Sciences of Ukraine, Kharkiv 61002
  • С. М. Десенко Institute of Single Crystals, National Academy of Sciences of Ukraine, Kharkiv 61001
  • О. В. Шишкин Institute of Single Crystals, National Academy of Sciences of Ukraine, Kharkiv 61001
  • Р. И. Зубатюк Institute of Single Crystals, National Academy of Sciences of Ukraine, Kharkiv 61001

DOI:

https://doi.org/10.1007/7556

Keywords:

3-amino-5-methylpyrazole, 3-amino-5-methylthio-1, 2, 4-triazole, dialkyl ketones, 3, 5-diamino-1, Meldrum's acid, pyrazolo[3, 4-b]pyridin-6-ones, 1, 4-triazolo[1, 5-a]pyrimidin-7-ones, X-ray structural analysis

Abstract

Interaction of 3-amino-5-methylpyrazole, 3-amino-5-methylthio-, and 3,5-diamino-1,2,4-triazole with Meldrum's acid, acetone, ethyl methyl ketone, and cyclohexanone leads to alkyl-substituted pyrazolo[3,4-b]pyridin-6-ones and 1,2,4-triazolo[1,5-a]pyrimidin-7-ones respectively.  The structure of 5,5-dimethyl-2-methylthio-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidin-7-one was demonstrated by an X-ray structural investigation.

How to Cite
Lipson, V. V.; Borodina, V. V.; Shirobokova, M. G.; Desenko, S. M.; Shishkin, O. V.; Zubatyuk, R. I.  Chem. Heterocycl. Compd. 2007, 43, 490. [Khim. Geterotsikl. Soedin. 2007, 595.]

For this article in the English edition see DOI 10.1007/s10593-007-0071-4


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Published

2023-03-24

Issue

No. 4 (2007)

Section

Original Papers