<i>cis-trans</i>-CONVERSION OF THE BICYCLE IN PYRROLIZIDINES: THE EFFECT OF THE PREFERRED CONFORMATIONS ON THE PROPERTIES OF THE BASES AND THE THERMODYNAMICS OF CONFORMATIONAL TRANSFORMATION OF THE RING FUSION TYPE

Authors

  • И. М. Скворцов State Scientific-Research Institute of Industrial Ecology, Saratov

DOI:

https://doi.org/10.1007/7769

Keywords:

conformers, pyrrolizidines, trans-fused pyrrolizidines, cis-trans conversion, thermodynamics

Abstract

The cis-trans conversion in pyrrolizidines and the  deciding  effect of steric factors on their conformational equilibrium are discussed. Work on  the synthesis and characteristics of  sterically strained pyrrolizidines is analyzed and  discussed.  It  is shown that such compounds (predominantly trans-fused)  have  a series of features in their properties that greatly distinguish them from unstrained pyrrolizidines. The first results from study of  the thermodynamics of cis-trans conversion of the pyrrolizidine bicycle are summarized.

How to Cite
Skvortsov, I. M.  Chem. Heterocycl. Compd. 2006, 42, 1247. [Khim. Geterotsikl. Soedin. 2006, 1443.]

For this article in the English edition see DOI 10.1007/s10593-006-0235-7


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Published

2023-05-03

Issue

No. 10 (2006)

Section

Review Articles