HYDRATED IMIDAZOLINE RING EXPANSION REACTION IN 2,3-DIHYDRO-9<i>H</i>-DIBENZO[<i>b</i>,<i>f</i>]IMIDAZO[2,1-<i>d</i>][1,5]OXAZOCINONE DERIVATIVES

Authors

  • Мария С. Расторгуева Institute of Chemistry, Saint Petersburg State University, 26 Universitetskii Ave., Petergof, Saint Petersburg 198504, R
  • Данил И. Вебер Institute of Chemistry, Saint Petersburg State University, 26 Universitetskii Ave., Petergof, Saint Petersburg 198504, R
  • Александр В. Сапегин Institute of Chemistry, Saint Petersburg State University, 26 Universitetskii Ave., Petergof, Saint Petersburg 198504, R

DOI:

https://doi.org/10.1007/7786

Keywords:

[1, 5, 8]oxadiazacycloundecin-9(6H)-ones, 5]oxazocines, expansion reaction of hydrated imidazoline, imidazoline-annulated systems.

Abstract

The possibility of expanding a hydrated imidazoline fragment in 2,3-dihydro-9H-dibenzo[b,f]imidazo[2,1-d][1,5]oxazocines was demonstrated for the first time, which granted access to 6,11-dihydro-12H-dibenzo[b,f][1,5]oxazocin-12-one derivatives, previously undescribed compounds with medium-sized rings. In addition, it was shown that imidazooxazocines underwent expansion reactions more readily than their seven-membered analogs.

 

Author Biography

Александр В. Сапегин, Institute of Chemistry, Saint Petersburg State University, 26 Universitetskii Ave., Petergof, Saint Petersburg 198504, R

к.х.н., доцент, Кафедра медицинской химии,Лаборатория синтеза биоактивных малых молекул

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Published

2023-11-01

Issue

Vol. 59 No. 9/10 (2023)

Section

Original Papers