SYNTHESIS AND ANTITUBERCULOTIC ACTIVITY OF SOME NEW IMIDAZO[4,5-<i>b</i>]PYRIDINE DERIVATIVES

Authors

  • L. Bukowski Department of Organic Chemistry Medical University of Gdańsk, 80-416 Gdańsk
  • Z. Zwolska Department of Microbiology Institute of Tuberculosis and Pulmonary Diseases, 01-138 Warszawa
  • E. Augustynowicz-Kopeć Department of Microbiology Institute of Tuberculosis and Pulmonary Diseases, 01-138 Warszawa

DOI:

https://doi.org/10.1007/7792

Keywords:

hydrazones, imidazo[4, 5-b]pyridine, pyrido[3', 2', 4, 5]imidazo[1, 2-d][1, 2, 4]triazine, thiosemicarbazones, antituberculotic activity

Abstract

The reactions of 2-acetylimidazo[4,5-b]pyridine hydrazone with  some alkyl-, arylisothiocyanates and some orthoesters were carried out. Various new derivatives of the titled compound  like thiosemicarbazones, ethoxymethylenehydrazones, and derivatives of the new pyrido[3',2':4,5]imidazo[1,2-d][1,2,4]triazine ring system were obtained. Biological data for selected compounds are presented.

How to Cite
Bukowski, L.; Zwolska, Z.; Augustynowicz-Kopeć, E.  Chem. Heterocycl. Compd. 2006, 42, 1358. [Khim. Geterotsikl. Soedin. 2006, 1571.]

For this article in the English edition see DOI 10.1007/s10593-006-0249-1

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Published

2023-05-16

Issue

No. 10 (2006)

Section

Original Papers