EFFICIENT SYNTHESIS OF BENZIMIDAZOLYLPHENOXYACETIC ACID O-ACETYLXYLOPYRANOSYL AND O-ACETYLGALACTOPYRANOSYL ESTERS AND THEIR ANTIVIRAL ACTIVITY

Authors

  • H. Chen Department of Applied Chemistry, Guangdong Ocean University, Zhanjiang 524088
  • W. Song Department of Applied Chemistry, Guangdong Ocean University, Zhanjiang 524088
  • S. Huang Department of Applied Chemistry, Guangdong Ocean University, Zhanjiang 524088

DOI:

https://doi.org/10.1007/7945

Keywords:

O-acetylgalactopyranosyl esters, O-acetylxylopyranosyl esters, benzimidazolylphenoxyacetic acid esters, tobacco mosaic virus, DMAP/Et3N.

Abstract

Six benzimidazolylphenoxyacetic acid O-acetylxylopyranosyl and O-acetylgalactopyranosyl esters were synthesized through esterification reactions at room temperature using 4-dimethylaminopyridine as a catalyst and triethylamine as a deacidification reagent. Their structure was confirmed by IR, 1H NMR spectra, MS, and elemental analysis. The synthesized compounds are all of β-configuration. The results show that DMAP is an effective catalyst; the yields can reach 63.6%. The
above esters showed an improved antiviral activity against tobacco mosaic virus.

How to Cite
Chen, H.; Song, W.; Huang, S.  Chem. Heterocycl. Compd. 2006, 42, 726. [Khim. Geterotsikl. Soedin. 2006, 832.]

For this article in the English edition see DOI 10.1007/s10593-006-0152-9

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Published

2023-08-14

Issue

No. 6 (2006)

Section

Original Papers