CYCLIZATION PRODUCTS OF N-FLUOROPHENYL-β-ALANINES AND THEIR PROPERTIES

Authors

  • Р. Вайцкялёнене Kaunas University of Technology, Kaunas LT-50254
  • В. Мицкявичюс Kaunas University of Technology, Kaunas LT-50254

DOI:

https://doi.org/10.1007/7951

Keywords:

dihydropyrimidinones, N-substituted β-alanines, 4-carboxy-2-pyrrolidinones, tetrahydropyridone, condensation

Abstract

Interaction of 2- and 4-fluorophenylamines with acrylic and itaconic acids leads to the synthesis of the corresponding N-substituted  β-alanines, the cyclization of which leads to derivatives of dihydropyrimidinone, 4-carboxy-2-pyrrolidinone, and tetrahydropyridone. Compounds having benzimidazole, pyrazole, and hydrazine fragments in the molecule have been obtained from 4-carboxy-1-(4-fluorophenyl)-2-pyrrolidinone.

How to Cite
Vaickelioniene, R.; Mickevicius, V.  Chem. Heterocycl. Compd. 2006, 42, 753. [Khim. Geterotsikl. Soedin. 2006, 862.]

For this article in the English edition see DOI 10.1007/s10593-006-0157-4

 

Published

2023-08-14

Issue

Section

Original Papers