4-HYDROXY-2-QUINOLONES. 90. SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF 4-METHYL-2-THIAZOLYLAMIDES OF HALO-SUBSTITUTED 4-HYDROXY-2-OXO-1,2-DIHYDRO-3-QUINOLINECARBOXYLIC ACIDS

Authors

  • И. В. Украинец National Pharmaceutical University, 61002 Kharkov
  • Л. В. Сидоренко National Pharmaceutical University, 61002 Kharkov
  • Л. А. Петрушова National Pharmaceutical University, 61002 Kharkov
  • О. В. Горохова National Pharmaceutical University, 61002 Kharkov

DOI:

https://doi.org/10.1007/8083

Keywords:

amides, 2-amino-4-methylthiazole, 4-hydroxy-2-oxo-1, 2-dihydro-3-quinolinecarboxylic acids, antitubercular activity

Abstract

Several variants were studied for the synthesis of esters of halogen derivatives of 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acids, whose reaction with 2-amino-4-methylthiazole gives the corresponding hetarylamides. Results are given for  a study of the antitubercular activity of these products.

How to Cite
Ukrainets, I. V.; Sidorenko, L. V.; Petrushova, L. A.; Gorokhova, O. V.  Chem. Heterocycl. Compd. 2006, 42, 64. [Khim. Geterotsikl. Soedin. 2006, 71.]

For this article in the English edition, see DOI 10.1007/s10593-006-0048-8

 

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Published

2023-09-20

Issue

No. 1 (2006)

Section

Original Papers