SYNTHESIS OF A NEW POLYHETEROCYCLIC SYSTEM – PYRAZOLO[5',1':2,3]PYRIMIDO[1,6-<i>a</i>]BENZIMIDAZOLE

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry, Ukraine National Academy of Sciences, Kiev 02094
  • М. О. Лозинский Institute of Organic Chemistry, Ukraine National Academy of Sciences, Kiev 02094

DOI:

https://doi.org/10.1007/8145

Keywords:

benzimidazoles, hydrazones, pyrimidines, trifluoroacetyl anhydride, acylation, recyclization, cyclocondensation

Abstract

Cyanoethylhydrazones of 2-aroylmethyl-1H-benzimidazoles  undergo recyclization on reaction with trifluoroacetyl  anhydride to give 3-aryl-1-cyanoethyl-5-(2-trfluoroacetaminoanilino)pyrazoles. The recyclization products may be  cyclized  with  closing  of the benzimidazole ring in two ways: with formation of 1-(5-pyrazolyl)benzimidazoles or 5,6-dihydroderivatives of a new polyheterocyclic system –
pyrazolo[5',1':2,3]pyrimido[1,6-a]benzimidazole.

How to Cite
Dzvinchuk, I. B.; Lozinskii, M. O.  Chem. Heterocycl. Compd. 2005, 41, 1419. [Khim. Geterotsikl. Soedin. 2005, 1685.]

For this article in the English edition, see DOI 10.1007/s10593-006-0012-7


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Published

2023-10-17

Issue

No. 11 (2005)

Section

Original Papers