CHARACTERISTICS OF THE SYNTHESIS OF SUBSTITUTED AND CONDENSED 2-METHYL-1,3-DIAZOLES

Authors

  • А. Ю. Лякина M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997
  • И. В. Михура M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997
  • И. С. Попова M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997
  • А. А. Формановский M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997

DOI:

https://doi.org/10.1007/8230

Keywords:

α-bromo ketones, dioxane dibromide, 2-methyl-1, 3-thiazoles, thioacetamide, Hantzsch condensation

Abstract

Condensation of aliphatic and carbocyclic α-bromo ketones with thioacetamide in ethanol usually leads to substituted or condensed 2-methyl-1,3-thiazoles. However in a number of cases the required compounds are only obtained in pyridine.

How to Cite
Liakina, A. Yu.; Mikhura, I. V.; Popova, I. S.; Formanovsky, A. A.  Chem. Heterocycl. Compd. 2005, 41, 1066. [Khim. Geterotsikl. Soedin. 2005, 1244.]

For this article in the English edition, see DOI 10.1007/s10593-005-0281-6


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Published

2023-10-30

Issue

No. 8 (2005)

Section

Original Papers