ADDITION OF NITRILE OXIDES TO ARYL ALLYL ETHERS

Authors

  • E. Alksnis Latvian Institute of Organic Synthesis, Riga LV 1006
  • V. Muravenko Latvian Institute of Organic Synthesis, Riga LV 1006
  • V. Dirnens Latvian Institute of Organic Synthesis, Riga LV 1006
  • E. Lukevics Latvian Institute of Organic Synthesis, Riga LV 1006

Keywords:

aryl allyl ethers, isoxazolines, nitrile oxides, hydroxamic acid chlorides

Abstract

3,5-Disubstituted isoxazolines with an aryloxymethyl group in position 5 have been synthesized. The [2+3] cycloaddition reaction of benzonitrile oxide to a 5-chlorosalicylic acid derivative containing two allyl groups occurs to give a compound with an oxazolinylmethyl fragment both in the ester and the ether parts of the molecule. The addition of nitrile oxides to the aryl allyl ethers occurs regiospecifically to give the 5-substituted isomer.

How to Cite
Alksnis, E.; Muravenko, V.; Dirnens, V.; Lukevics, E. Chem. Heterocycl. Compd. 2004, 40, 797. [Khim. Geterotsikl. Soedin. 2004, 928.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000040778.88220.e3

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Published

2004-06-25

Issue

No. 6 (2004)

Section

Original Papers