STEREODIRECTED CATALYTIC SYNTHESIS OF PERHYDROACRIDINES AND THEIR ISOLOGS FROM DECAHYDROACRIDINE-1,8-DIONES

Authors

  • Т. Г. Николаева N. G. Chernyshevskii Saratov State University, Sarato
  • Ю. М. Щекотихин "Nita-Farm", Saratov 410005

Keywords:

8-hydroxydodecahydroacridin-1-ones, decahydroacridine-1,8-diones, perhydroacridines, catalytic hydrogenation, stereochemistry

Abstract

The catalytic reduction of decahydroacridine-1,8-diones has been studied under hydrogen pressure in the presence of Raney nickel and with nascent hydrogen from alkaline treatment of nickel–aluminum alloy. Conditions have been developed for the stereodirected synthesis of 8-hydroxy-cis-dodecahydroacridin-1-ones and perhydroacridines of the cis-syn-cis and cis-anti-cis configurations. The structure of the hydroacridines was established by 1H NMR spectroscopy, 13C, and IR spectra, and chromato-mass spectrometry.

How to Cite
Nikolaeva, T. G.; Shchekotikhin, Yu. M. Chem. Heterocycl. Compd. 2004, 40, 582. [Khim. Geterotsikl. Soedin. 2004, 693.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000037313.98113.1e

Downloads

Published

2004-05-25

Issue

No. 5 (2004)

Section

Original Papers