SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SUBSTITUTED 5-CYANO-6-OXO-2-STYRYLNICOTINIC ACIDS

Authors

  • А. Б. Деянов Perm State Pharmaceutical Academy, Perm 614990
  • М. Е. Коньшин Perm State Pharmaceutical Academy, Perm 614990

Keywords:

anilides, hydrazides, 5-cyano-6-oxo-2-(substituted styryl)nicotinic acid, esters, antimicrobial activity, synthesis

Abstract

Derivatives of the anilide or ethyl ester of 5-cyano-6-oxo-2-styrylnicotinic acid are formed in the reaction of the anilide or ethyl ester of 5-cyano-2-methyl-6-oxonicotinic acid with aromatic aldehydes. On interaction with hydrazine hydrate the products are converted into hydrazides of 5-cyano-6-oxo-2-styrylnicotinic acid derivatives.

How to Cite
Deyanov, A. B.; Konshin, M. E. Chem. Heterocycl. Compd. 2004, 40, 452. [Khim. Geterotsikl. Soedin. 2004, 547.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000033536.31601.cb

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Published

2004-04-25

Issue

No. 4 (2004)

Section

Original Papers