CONVERSION OF AMINO GROUP IN POSITION 6 OF URACIL

Authors

  • А. А. Яволовский A. V. Bogatsky Physico-Chemical Institute, Ukraine National Academy of Sciences, Odessa 65080
  • Э. И. Иванов A. V. Bogatsky Physico-Chemical Institute, Ukraine National Academy of Sciences, Odessa 65080

Keywords:

5,6-dihydroxydiiminouracil, 6-hydroxyaminouracil, 5-nitroso-6-phenylhydrazinouracil, 1,2,5-oxadiazolo- and 1,2,3-triazolo[3,4-d]pyrimidine N-oxides, nucleophilic substitution, oxidation

Abstract

The possibility of substituting amino groups in position 6 of 5-R-uracils (R = H, NO) by hydroxylamine and phenylhydrazine has been demonstrated. The products of substitution – 6-hydroxyaminouracil, 5,6-dihydroxydiiminouracil, and 5-nitroso-6-phenylhydrazinouracil – are readily oxidized into 1,2,5-oxadiazolo- and 1,2,3-triazolo[3,4-d]pyrimidine N-oxides respectively.

How to Cite
Yavolovskii, A. A.; Ivanov, E. I. Chem. Heterocycl. Compd. 2004, 40, 361. [Khim. Geterotsikl. Soedin. 2004, 443.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000028633.76885.60

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Published

2004-03-25

Issue

No. 3 (2004)

Section

Original Papers