REGIOISOMERIC ACETOXY DERIVATIVES OF 8-AZA-D-HOMOGONA-12,17a-DIONE. ANNELATION OF 1-METHYL-3,4-DIHYDROISOQUINOLINE WITH 4-ACETOXY-2-ACETYLCYCLOHEXANE-1,3-DIONE

Authors

  • О. В. Гулякевич Institute of Bioorganic Chemistry, National Academy of Sciences of the Republic of Belarus, Minsk 220141
  • В. Г. Зайцев Institute of Bioorganic Chemistry, National Academy of Sciences of the Republic of Belarus, Minsk 220141
  • А. Л. Михальчук Institute of Bioorganic Chemistry, National Academy of Sciences of the Republic of Belarus, Minsk 220141

Keywords:

8-aza-D-homogonanes, 8-azasteroids, 2-acylcyclohexane-1,3-diones, 3,4-dihydroisoquinolines, cyclic Schiff's bases, annelation, regioselectivity, stereochemistry

Abstract

Annelation ([2+4] cyclocondensation) of 1-methyl-3,4-dihydroisoquinoline with 4-acetoxy-2-acetyl-cyclohexane-1,2-dione leads to a mixture of regioisomeric acetoxy derivatives of 9-methyl-8-aza-8-aza-D-homogonanes-homogona-12,17a-dione.

How to Cite
Gulyakevich, O. V.; Zaitsev, V. G.; Mikhal'chuk, A. L. Chem. Heterocycl. Compd. 2004, 40, 315. [Khim. Geterotsikl. Soedin. 2004, 389.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000028627.77366.49

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Published

2004-03-25

Issue

No. 3 (2004)

Section

Original Papers