SYNTHESIS OF SOME HALOGEN- AND NITRO-SUBSTITUTED NICOTINIC ACIDS AND THEIR FRAGMENTATION UNDER ELECTRON IMPACT
Keywords:
halo and nitro derivatives, nicotinic acids, fragmentation under electron impactAbstract
Features of electrophilic and nucleophilic substitution under chlorination and nitration reactions conditions have been investigated for 6-hydroxy- and 6-methyl-substituted derivatives of 3-cyano-4-methyl-2(1H)-pyridones. The polychloro- and nitro-substituted 3-cyano-4-methylpyridines obtained were used as synthons in the synthesis of some polyhalo- and nitro-substituted nicotinic acids and their amides. The fragmentation pathways of the synthesized compounds under electron impact have been studied.
How to Cite
Dyadyuchenko, L. V.; Strelkov, V. D.; Mikhailichenko, S. N.; Zaplishny, V. N. Chem. Heterocycl. Compd. 2004, 40, 308. [Khim. Geterotsikl. Soedin. 2004, 381.]
For this article in the English edition, see DOI 10.1023/B:COHC.0000028626.45566.67