NITROPYRIDINES. 1. HANTZSCH SYNTHESIS OF NITROPYRIDINES AND THEIR QUATERNARY SALTS
Keywords:
5-nitro-1,4-dihydropyridines, nitropyridines, quaternary salts of nitropyridinesAbstract
Previously unknown 1,4-dihydropyridines containing acetyl, amide, benzoyl, ester, and cyano groups together with a nitro group were synthesized with preparative yields by a two-component Hantzsch synthesis based on 2-nitro-1,3-diphenylpropenone and various enamines. The nitrodihydropyridines were aromatized with sodium nitrite in acetic acid. The quaternary salts of low-basicity pyridines were produced with dimethyl sulfate and methyl fluorosulfonate.
How to Cite
Sagitullina, G. P.; Glizdinskaya, L. V.; Sitnikov, G. V.; Sagitullin, R. S. Chem. Heterocycl. Compd. 2002, 38, 1336. [Khim. Geterotsikl. Soedin. 2002, 1518.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1022174325051