DI-6R,7R<sup>1</sup>-4(3H)-OXO-2-QUINAZOLINYL-SUBSTITUTED CYCLOBUTANES FROM PINIC AND <i>sym</i>-HOMOPINIC ACIDS

Authors

  • Ф. Авотиньш Riga Technical University, Riga LV-1658
  • М. Петрова Riga Technical University, Riga LV-1658
  • А. Страков Riga Technical University, Riga LV-1658

Keywords:

N-acyl derivatives of 5-bromo-, 4-chloro-, and 4,5-dimethoxyanthranilic acids, sym-homopinic acid, di-6,7-substituted 4(3H)-oxo-2-quinazolinyl derivatives of cyclobutane, pinic acid

Abstract

The corresponding diamides were obtained from reaction of cis-3-carboxy-2,2-dimethylcyclobutylacetic acid (pinic acid) and of cis/trans-3-(carboxymethyl)-2,2-dimethylcyclobutyl-acetic acid (homopinic acid) dichlorides with two equivalents of 5-bromo-, 4-chloro-, and 4,5-dimethoxyanthranilic acids. Treatment of them with formamide leads to the formation of the corresponding 2,2-dimethyl-3-[4(3H)-oxo-2-quinazolinyl]methyl-1-[4(3H)-oxo-2-quinazolinyl]cyclobutanes and 2,2-dimethyl-1,3-di[4(3H)-oxo-2-quinazolinylmethyl]cyclobutanes.

How to Cite
Avotin'sh, F.; Petrova, M.; Strakovs, A. Chem. Heterocycl. Compd. 2002, 38, 817. [Khim. Geterotsikl. Soedin. 2002, 926.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1020633720890

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Published

2002-07-25

Issue

No. 7 (2002)

Section

Original Papers