CYCLOCONDENSATION OF 2-AMINO-1,3,4-THIADIAZOLES WITH β-SULFONYLVINYLTRIFLUOROMETHYLDIOLS

Authors

  • А. Л. Красовский M. V. Lomonosov Moscow State University, 119899 Moscow
  • А. M. Моисеев M. V. Lomonosov Moscow State University, 119899 Moscow
  • В. Г. Ненайденко M. V. Lomonosov Moscow State University, 119899 Moscow
  • E. C. Баленкова M. V. Lomonosov Moscow State University, 119899 Moscow

Keywords:

2-amino-1,3,4-thiadiazole, 6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidines, β-sulfonylvinyltrifluoromethyldiols, cyclocondensation

Abstract

A series of CF3-containing 6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-ols was obtained by the interaction of 2-amino-1,3,4-thiadiazoles with β-sulfonylvinyltrifluoromethyldiols and their stereochemistry was established. The structure of 5-(phenylsulfonyl)-7-(trifluoromethyl)-6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-ol was confirmed by X-ray crystallography.

How to Cite
Krasovsky, A. L.; Moiseev, A. M.; Nenajdenko, V. G.; Balenkova, E. S. Chem. Heterocycl. Compd. 2002, 38, 231. [Khim. Geterotsikl. Soedin. 2002, 253.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1015303712382

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Published

2002-02-25

Issue

No. 2 (2002)

Section

Original Papers