SYNTHESIS AND ALKYLATION OF PIPERIDINIUM 4,5-<i>trans</i>-3-CYANO-6-HYDROXY-4-(2-IODOPHENYL)-6-METHYL-5-(2-METHYLPHENYL)CARBAMOYL-1,4,5,6-TETRAHYDROPYRIDINE-2-THIOLATE. MOLECULAR AND CRYSTAL STRUCTURE OF 3-(2-IODOPHENYL)-2-(4-PHENYL-2-THIAZOLYL)ACRYLONITRILE

Authors

  • С. Г. Кривоколыско Taras Shevchenko Lugansk State Pedagogical University, 348011 Lugansk
  • В. Д. Дяченко Taras Shevchenko Lugansk State Pedagogical University, 348011 Lugansk
  • В. Н. Нестеров A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 117813 Moscow
  • В. П. Литвинов N. D. Zelinsky Institute of Organic Chemistry, 117913 Moscow

Keywords:

N-acetoacetyl-o-toluidine, o-iodobenzaldehyde, 3-(2-iodophenyl)-2-(4-phenyl-2-thiazolyl)acylonitrile, cyanothioacetamide, condensation, X-ray diffraction structural analysis

Abstract

The reaction of o-iodobenzaldehyde, cyanothioacetamide, and N-acetoacetyl-o-toluidine in the presence of piperidine gave piperidinium 4,5-trans-3-cyano-6-hydroxy-4-(2-iodophenyl)-6-methyl-5-(2-methylphenyl)carbamoyl-1,4,5,6-tetrahydropyridine-2-thiolate used in the synthesis of substituted 4,5-trans-2-alkylthiotetrahydropyridines and 2-(2-thiazolyl)acrylonitriles. The structure of 3-(2-iodophenyl)-2-(4-phenyl-2-thiazolyl)acrylonitrile was studied using X-ray diffraction structural analysis.

How to Cite
Krivokolysko, S. G.; Dyachenko, V. D.; Nesterov, V. N.; Litvinov, V. P. Chem. Heterocycl. Compd. 2001, 37, 855. [Khim. Geterotsikl. Soedin. 2001, 929.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1012499424379

Downloads

Published

2001-07-25

Issue

No. 7 (2001)

Section

Original Papers