Investigation of Nitrogen- and Sulfur-containing Heterocycles. 53. Reactions of 5-Amino-6-mercaptopyrimidines with Derivatives of <i>p</i>-Chloronitrobenzene. Synthesis of a New Heterocyclic System – Pyrimido[4,5-<i>b</i>]-1,4-benzothiazepine

Authors

  • Т. С. Сафонова Center for Chemistry of Medicines - All-Russian Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815
  • М. П. Немерюк Center for Chemistry of Medicines - All-Russian Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815
  • Н. А. Гринева Center for Chemistry of Medicines - All-Russian Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815
  • М. А. Керемов Dagestan State University, Makhachkala 367010
  • М. М. Лиховидова Center for Chemistry of Medicines - All-Russian Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815

Keywords:

aminomercaptopyrimidines, pyrimido[4,5-b]-1,4-benzthiazepine, pyrimidylarylamines, pyrimidyl aryl sulfides, Smiles rearrangement

Abstract

A series of pyrimidylaryl sulfides have been obtained by the interaction of 5-amino-6-mercaptopyrimidines with p-nitrochlorobenzene derivatives containing a carbonyl function. The properties and cyclization routes of pyrimidylaryl sulfides into derivatives of a new tricyclic system, pyrimido[4,5-b]-1,4-benzothiazepine, have been studied.

How to Cite
Safonova, T. S.; Nemeryuk, M. P.; Grineva, N. A.; Keremov, M. A.; Likhovidova, M. M. Chem. Heterocycl. Compd. 2001, 37, 245. [Khim. Geterotsikl. Soedin. 2001,270.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1017531903175

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Published

2001-02-25

Issue

No. 2 (2001)

Section

Original Papers