NEW METHODOLOGY OF FUNCTIONALIZATION OF THE IMIDAZOLE RING BY ALKYNES

Авторы

  • B. A. Trofimov A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of Russian Academy of Sciences
  • L. V. Andriyankova A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of Russian Academy of Sciences
  • K. V. Belyaeva A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1309

Ключевые слова:

carbenes, electron-deficient acetylenes, imidazoles, zwitterions, functionalization, multicomponent reactions, nucleophilic addition, (C-2)-vinylation

Аннотация

A new methodology for functionalization of the imidazole ring via the zwitterionic intermediates and their carbene tautomers generated by nucleophilic addition of 1-substituted imidazoles to electron-deficient acetylenes followed by the reactions with appropriate electrophiles is discussed.

Also published in Chemistry of Heterocyclic Compounds, 2012, 48 (1), pp 147-154

http://link.springer.com/article/10.1007/s10593-012-0978-2

Загрузки

Опубликован

2013-12-05

Выпуск

№ 1 (2012)

Раздел

Обзорные статьи