AT THE CROSSROADS OF HETEROCYCLIC AND PEPTIDE CHEMISTRIES. THE AMINOACYL INCORPORATION REACTION IN THE SYNTHESIS OF MEDIUM-SIZED RING HETEROCYCLES

Авторы

  • V. N. Azev Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute
  • A. N. Chulin Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute
  • I. L. Rodionov Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute

DOI:

https://doi.org/10.1007/1461

Ключевые слова:

aminoacyl lactams, cyclol, dioxodiazacycloalkanes, trioxotriazacycloalkanes, aminoacyl incorporation, medium-sized ring, synthetic backbone scaffold

Аннотация

Aminoacyl incorporation reaction of peptides is considered in the context of synthetic heterocyclic chemistry with the particular emphasis on scope, mechanism and major by-products of the reaction. Medium-sized mono and bicyclic molecules available via aminoacyl incorporation reaction are unique building blocks with significant promise in biomolecular design.

How to Cite
Azev, V. N.; Chulin, A. N.; Rodionov, I. L. Chem. Heterocycl. Compd. 2014, 50, 145. [Khim. Geterotsikl. Soedin. 2014, 166.]

For this article in the English edition see DOI 10.1007/s10593-014-1457-8

Биографии авторов

V. N. Azev, Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute

Viatcheslav Nikolaevich Azev

A. N. Chulin, Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute

Alexey Nikolaevich Chulin

I. L. Rodionov, Branch of Shemyakin and Ovchinnikov Bioorganic Chemistry Institute

Igor Leonidovich Rodionov

Загрузки

Опубликован

2014-02-28

Выпуск

№ 2 (2014)

Раздел

Обзорные статьи