ONE-POT SYNTHESIS OF TRISUBSTITUTED PYRAZOLES VIA MULTICOMPONENT APPROACH

Авторы

  • P. Santhosh Department of Chemistry, National Institute of Technology
  • V. S. R. Chunduru Department of Chemistry, National Institute of Technology
  • V. Rajeswar Rao Department of Chemistry, National Institute of Technology

DOI:

https://doi.org/10.1007/2071

Ключевые слова:

acetylacetone, 3-(2-bromoacetyl)coumarins, hydrazine hydrate, phenacyl bromides, pyrazole, one-pot, multicomponent reactions

Аннотация

An efficient one-pot multicomponent reaction for the synthesis of substituted 1-aryl- or 1-heteryl-substituted 3,5-dimethylpyrazoles with excellent yields has been described. Reaction of 3-(2-bromoacetyl)coumarins or phenacyl bromides with acetylacetone and hydrazine hydrate in ethanol afforded the corresponding 3,5-dimethylpyrazoles in good yields. All the synthesized compounds were characterized by their analytical and spectral data.

How to Cite
Santhosh, P.; Chunduru, V. S. R.; Rajeswar Rao, V. Chem. Heterocycl. Compd. 2011, 47(4), 448. [Khim. Geterotsikl. Soedin. 2011, 547.]

For this article in the English edition see DOI 10.1007/s10593-011-0779-z

Загрузки

Опубликован

2014-11-27

Выпуск

№ 4 (2011)

Раздел

Оригинальные статьи