GREEN AND CATALYST-FREE ONE-POT SYNTHESIS OF 2,3-DIHYDROQUINAZOLIN-4(1<i>H</i>)-ONES IN WATER

Авторы

  • Abolfazl Olyaei Department of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran
  • Fatemeh Rahbarian Department of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran
  • Mahdieh Sadeghpour Department of Chemistry, College of Science, Takestan Branch, Islamic Azad University, Takestan

DOI:

https://doi.org/10.1007/2644

Ключевые слова:

isatoic anhydride, aromatic aldehyde, dihydroquinazolinone

Аннотация

A facile and highly efficient protocol was successfully applied to synthesize mono- and disubstituted dihydroquinazolinones through a three-component coupling reaction of isatoic anhydride, aniline or ammonium acetate, and aromatic aldehydes in refluxing water with excellent yield without using any catalysts. The protocol avoids the use of hazardous solvents and chromatographic separation. The generality and functional tolerance of this convergent and environmentally benign method is demonstrated.

How to Cite
Olyaei, A.; Rahbarian, F.; Sadeghpour, M. Chem. Heterocycl. Compd. 2015, 51, 899. [Khim. Geterotsikl. Soedin. 2015, 51, 899.]

For this article in the English edition see DOI 10.1007/s10593-015-1793-3

Загрузки

Опубликован

2015-10-29

Выпуск

Том 51 № 10 (2015)

Раздел

Оригинальные статьи