FACILE SYNTHESIS OF THE AZOCINO[4,3-<i>b</i>]INDOLE FRAMEWORK OF STRYCHNOPIVOTINE AND OTHER <i>Strychnos</i> ALKALOIDS

Авторы

  • Nesimi Uludag Department of Chemistry, Namık Kemal University, 59030 Tekirdag
  • Recep Yılmaz Department of Chemistry, Namık Kemal University, 59030 Tekirdag
  • Oktay Asutay Department of Chemical Technology, Namık Kemal University, 59700 Muratlı/Tekirdag
  • Naki Colak Department of Chemistry, Hitit University, 19030 Corum

DOI:

https://doi.org/10.1007/3043

Ключевые слова:

1, 5-methanoazocino[4, 3-b]indole, Strychnos alkaloids

Аннотация

A new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps.

How to Cite
Uludag, N.; Yılmaz, R.; Asutay, O.; Colak, N. Chem. Heterocycl. Compd. 2016, 52, 196. [Khim. Geterotsikl. Soedin. 2016, 52, 196.]

For this article in the English edition see DOI 10.1007/s10593-016-1860-4

Биография автора

Nesimi Uludag, Department of Chemistry, Namık Kemal University, 59030 Tekirdag

organic division

Загрузки

Опубликован

2016-04-11

Выпуск

Том 52 № 3 (2016)

Раздел

Оригинальные статьи