AN EFFICIENT AND FACILE SYNTHESIS OF D-CYCLOSERINE SUBSTANTIALLY FREE FROM POTENTIAL IMPURITIES

Аннотация

An efficient and facile synthesis of D-cycloserine has been developed from D-serine with 61% overall yield employing protection-deprotection strategy. Different parameters affecting the impurities content and yield of D-cycloserine have been studied. Mild reaction conditions provided the product with remarkable purity (>99%) and high stability.