4-HYDROXYCOUMARINS AS MICHAEL DONORS IN ASYMMETRIC ROUTES TO POLYCYCLIC COUMARINS (MICROREVIEW)

Авторы

  • Mariagrazia Rullo Department of Pharmacy - Drug Sciences, University of Bari “A. Moro” Via E. Orabona 4, Bari 70125, Italy
  • Leonardo PISANI Department of Pharmacy - Drug Sciences, University of Bari “A. Moro” Via E. Orabona 4, Bari 70125, Italy

DOI:

https://doi.org/10.1007/4499

Ключевые слова:

4-hydroxycoumarins, fused coumarins, asymmetric synthesis, Michael addition.

Аннотация

Different [3,4]-fused polycyclic 2H-chromen-2-ones can be prepared in a stereoselective fashion starting from 4-hydroxycoumarins as nucleophilic synthones. Herein we report a brief overview of the most recent methods including Pd-catalyzed [3+3] annulation processes, organocatalytic one-pot and domino Michael addition/cyclization, tandem conjugate addition/hydroxyalkylation, and organocascade catalytic reaction.

Загрузки

Опубликован

2018-06-04

Выпуск

Том 54 № 4 (2018): Стереоселективный синтез гетероциклических соединений

Раздел

Гетероциклы в фокусе