SYNTHESIS AND CHARACTERIZATION OF NEW PYRIDO- AND PYRAZOLOPYRIMIDINE DERIVATIVES USING 2-SUBSTITUTED VINAMIDINIUM SALTS

Авторы

  • Abdolmohammad Mehranpour Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr 75169
  • Sedigheh Hashemnia Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr 75169
  • Mona Bornak Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr 75169

DOI:

https://doi.org/10.1007/5072

Ключевые слова:

pyrazolo[3, 4-b]pyridine, pyrazolo[1, 5-a]pyrimidine, pyrido[2, 3-d]pyrimidine, vinamidinium salts

Аннотация

Several novel pyrido- and pyrazolopyrimidine derivatives were readily synthesized by reaction of 6-aminouracil or 3(5)-aminopyrazole with 2-substituted vinamidinium salts. The reactions were carried out in a relatively short time without any base or catalyst. The structures of the synthesized compounds were confirmed by UV-vis, IR, and 1H and 13C NMR spectroscopy, as well as mass spectrometry and elemental analysis. The obtained results showed that tautomers of 3(5)-amino-1(H)-pyrazole can participate in the formation of the new pyrido- and pyrazolopyrimidine derivatives with their respective most nucleophilic centers N-2 and C-4.

Биография автора

Abdolmohammad Mehranpour, Chemistry Department, Faculty of Sciences, Persian Gulf University, Bushehr 75169

Chemistry department

Загрузки

Опубликован

2019-11-12

Выпуск

Том 55 № 11 (2019)

Раздел

Оригинальные статьи