SYNTHESIS OF NOVEL TETRAHYDROPYRIMIDO[4,5-<i>b</i>][1,6]NAPHTHYRIDINES <i>VIA</i> CONDENSATION OF 1-BENZYL-3,5-BIS[(<i>E</i>)-ARYLMETHYLIDENE]TETRAHYDROPYRIDIN-4(1<i>H</i>)-ONES WITH 6-AMINOURACILS

Авторы

  • Mehdi Ghandi School of Chemistry, College of Science, University of Tehran, Enghelab St., Tehran, Iran
  • Rasoul Rashid School of Chemistry, College of Science, University of Tehran, Enghelab St., Tehran, Iran
  • Alireza Abbasi University of Tehran

DOI:

https://doi.org/10.1007/5595

Ключевые слова:

6-aminouracils, 1-benzyl-4-piperidinone, 1, 6-naphthyridines.

Аннотация

The successful synthesis of novel tetrahydropyrimido[4,5-b][1,6]naphthyridine derivatives is reported. 1-Benzyl-3,5-bis[(E)-arylmethylidene]tetrahydropyridin-4(1H)-ones prepared via Knoevenagel condensation of 1-benzyl-4-piperidinone with aromatic aldehydes undergo condensation with 6-aminouracils in acetic acid to afford the desired products. Structures of the products are confirmed by analytical data and X-ray crystallography analysis.

Биографии авторов

Mehdi Ghandi, School of Chemistry, College of Science, University of Tehran, Enghelab St., Tehran, Iran

School of Chemistry, College of Science

Rasoul Rashid, School of Chemistry, College of Science, University of Tehran, Enghelab St., Tehran, Iran

School of Chemistry, College of Science

Alireza Abbasi, University of Tehran

School of Chemistry, College of Science

Загрузки

Опубликован

2020-11-26

Выпуск

Том 56 № 11 (2020)

Раздел

Оригинальные статьи