PHOTOREGULATED MACROCYCLIC CELL-PENETRATING PEPTIDES

Авторы

  • Igor V. Komarov Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv 01601, Ukraine
  • Iuliia V. Bakanovych Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv 01601, Ukraine

DOI:

https://doi.org/10.1007/5692

Ключевые слова:

macrocycles, cell-penetrating peptides, photoswitches, diarylethenes, azobenzenes, photopharmacology

Аннотация

Light-controlled cell-penetrating peptides are reviewed as emerging photopharmacology tools. Key discoveries made recently in this area demonstrated that photoregulation of the cell-penetrating ability is very efficient in structural contexts of (macro)heterocyclic peptidic molecules, containing azobenzene or diarylethene photoisomerizable moieties.

Биография автора

Igor V. Komarov, Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv 01601, Ukraine

Head of Supramolecular Chemistry Chair

Загрузки

Опубликован

2020-07-10

Выпуск

Том 56 № 6 (2020): Гетероциклические соединения в медицинской химии

Раздел

Гетероциклы в фокусе