SILVER-ASSISTED PALLADIUM-CATALYZED ONE-POT SYNTHESIS OF 3-(HETERO)ARYLMETHYL DERIVATIVES OF IMIDAZO[1,2-<i>a</i>]PYRIDINES
DOI:
https://doi.org/10.1007/5864Ключевые слова:
benzylimidazo[1, 2-a]pyridine, C–C coupling, 5-exo-dig cyclization, metal-catalyzed reactions, one-pot synthesis.Аннотация
3-(Hetero)arylmethyl derivatives of imidazo[1,2-a]pyridine have been synthesized by a novel one-pot method consisting of the Sonogashira coupling of tert-butyl prop-2-yn-1-yl(pyridin-2-yl)carbamate with different substituted (hetero)aryl bromides and cyclization of the in situ obtained intermediate substituted (hetero)aryl acetylene derivatives.Загрузки
Опубликован
2021-05-26
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Оригинальные статьи