SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW TRIAZINO-, TRIAZOLO-, AND PYRAZOLOPYRIDAZINE DERIVATIVES
DOI:
https://doi.org/10.1007/6622Ключевые слова:
diethyl malonate, ethyl acetoacetate, ethylbenzoylacetate, ethyl cyanoacetate, hydrazinopyridazine, phenacyl bromide, pyrazolopyridazine, triazinopyridazine, thiazolopyridazineАннотация
The reaction of 3-hydrazino-4,5,6-triphenylpyridazine with phenacyl bromide afforded triazolopyridazine, while the reaction with different aldehydes gave the corresponding 3-arylidene hydrazinopyridazine derivatives which, on the reaction with Br2/Na2CO3, gave the corresponding triazinopyridazines. Also, a fusion with ethyl acetoacetate, ethyl benzoylacetate, diethyl malonate or ethyl phenylacetoacetate gave the corresponding pyrazolo- and triazinopyridazine derivatives. The antimicrobial activity of some new compounds has been discussed.
How to Cite
Yassin, F. A. Chem. Heterocycl. Compd. 2009, 45, 997. [Khim. Geterotsikl. Soedin. 2009, 1253.]
For this article in the English edition see DOI 10.1007/s10593-009-0381-9
