SYNTHESIS OF SUBSTITUTED 1,3,4-OXADIAZOLE DERIVATIVES

Авторы

  • V. Mickevičius Kaunas University of Technology LT-50254 Kaunas
  • R. Vaickelionienė Kaunas University of Technology LT-50254 Kaunas
  • B. Sapijanskaitė Kaunas University of Technology LT-50254 Kaunas

DOI:

https://doi.org/10.1007/6828

Ключевые слова:

acid hydrazides, benzoyl chloride, 2-pyrrolidinone, substituted oxadiazoles, thionyl chloride, 5-thioxo-1, 3, 4-oxadiazoles

Аннотация

Monosubstituted oxadiazoles were synthesized by the reaction of hydrazides with triethyl orthoformate. Their reactions with benzoyl chloride gave benzoyl-carbohydrazides, which under the action of thionyl chloride were cyclized to the respective 2,5-disubstituted oxadiazoles.  1-Aryl-4-(5-thioxo-4,5-dihydro-1,3,4-oxa-
diazol-2-yl)pyrrolidin-2-ones were synthesized from acid hydrazides using carbon disulphide in the basic conditions.

How to Cite
Mickevičius, V.; aickelionienė, R. V; Sapijanskaitė, B.  Chem. Heterocycl. Compd. 2009, 45, 215. [Khim. Geterotsikl. Soedin. 2009, 269.]

For this article in the English edition see DOI 10.1007/s10593-009-0252-4

Загрузки

Опубликован

2022-05-25

Выпуск

№ 2 (2009)

Раздел

Оригинальные статьи