A NOVEL SYNTHESIS OF 1,8-ALKANОРYRIDO[З,4-<i>d</i>]PYRIDAZINE: NEW RING SYSTEM
Ключевые слова:
8-alkanopyrido[3,4-d]pyridаzinеs, cycloalkenopyridazines, cycloalkenopyridinesАннотация
Cycloalkylidenemalononitrdes couple with various diazonium salts to yield the corresponding cycloalkeno[c]pyridazines, which react with trichloro-acetonitrile to give the 1,8-alkanopyrido[3,4-d]pyridazines. The reaction of cycloalkenopyridazines with DMF dimethylacetal gives enamine derivatives, which can be converted to 1,8-alkanopyrido[3,4-d]pyridaziries via treating with hydrazine hydrate оr aromatic amines. Substituted cycloalkenopyridines react with diazoaminobenzene to afford the corresponding 1,8-aikanоpyridopyri-dazines.
How to Cite
Elassar, A. Z. A.; Elkholy, Y. M. Chem. Heterocycl. Compd. 2002, 38, 1521. [Khim. Geterotsikl. Soedin. 2002, 1722.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1022657914710